CTAP has been used as a ?-opioid receptor (MOR) antagonist: to study the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitor isoleucine-proline-isoleucine (IPI) and vildagliptin in carrageenan-induced inflammation to study the role of MOR in glutamate and gamma-aminobutyric acid (GABA) efflux during predator stress in ratsto determine the endogenous opioid peptide involved in blocking pain induced by activated gastrin-releasing peptide (Grp+) neurons
Biochem/physiol Actions
CTAP is a peptide antagonist produced from somatostatin analogs.