D-Cycloserine, synthetic

D-Cycloserine, synthetic

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Application

D-cycloserine has been used to inhibit serine hydroxymethyltransferase.

Biochem/physiol Actions

Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.Mode of Resistance: D-Ala transport interference.

General description

Chemical structure: amino acid derivatives

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Packaging

25, 100, 250 mg in poly bottle

mp147 °C (dec.) (lit.)
InChI keyDYDCUQKUCUHJBH-UWTATZPHSA-N
InChI1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
ManufacturerSIGMA-ALDRICH
Formpowder

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