4-Chloro-DL-phenylalanine methyl ester hydrochloride,
Application
4-Chloro-DL-phenylalanine methyl ester hydrochloride has been used to induce 5-hydroxytryptamine (5-HT) depletion in rats.
Biochem/physiol Actions
Tryptophan hydroxylase inhibitor. Crosses blood brain barrier better than p−chlorophenylalanine.
General description
4-Chloro-DL-phenylalanine methyl ester hydrochloride stimulates glucose intolerance in pregnant mice. Studies have shown that 4-Chloro-DL-phenylalanine methyl ester hydrochloride is associated with cognitive defects in rodents.
Packaging
1, 5, 25 g in poly bottle
| Quality Level | 200 |
|---|---|
| mp | 186-189 °C (lit.) |
| InChI key | GCBCWTWQAFLKJG-UHFFFAOYSA-N |
| InChI | 1S/C10H12ClNO2.ClH/c1-14-10(13)9(12)6-7-2-4-8(11)5-3-7;/h2-5,9H,6,12H2,1H3;1H |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | powder |
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