Thiamine pyrophosphate, >=95%

Descriptions

Application

Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.

Thiamine pyrophosphate has been used: for the preparation of chitosan nano-particles as a standard for vitamin B1 and its derivative in high-performance liquid chromatography (HPLC) analysis immunofluorescence

Biochem/physiol Actions

Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ?acceptor aldehyde?.

Packaging

1, 5, 25, 100 g in poly bottle

Specifications

Quality Level	200
InChI key	YXVCLPJQTZXJLH-UHFFFAOYSA-N
InChI	1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Solubility	H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless
Form	powder
Assay	≥95%