Uricase from Bacillus fastidiosus, lyophilized, approx. 9 U/mg
Application
Uricase may be used for the determination of uric acid in biological fluids. It may be helpful in the spectrophotometric determination of purines and purine nucleosides.
Biochem/physiol Actions
Uricase catalyzes the oxidation of uric acid to 5-hydroxyisourate, which subsequently forms (S)-allantoin. It is involved in purine metabolism, urate degradation and (S)-allantoin formation .
Other Notes
For the determination of uric acid in biological fluids; In the spectrophotometric determination of purines and purine nucleosides.
Unit Definition
1 U corresponds to the amount of enzyme which oxidizes 1 µmole uric acid at pH 9.1 and 37 °C.
| Quality Level | 300 |
|---|---|
| InChI key | VPXDHZMLJOJKOX-UHFFFAOYSA-N |
| InChI | 1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H, |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
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