Thymidine 5-monophosphate p-nitrophenyl ester sodium salt, >=98% (HPLC)
Application
Thymidine 5?-monophosphate p-nitrophenyl ester sodium salt has been used as a substrate for assessing phosphodiesterase activity. It is also been used as a nucleotide analog in the autotaxin inhibition assay.
Biochem/physiol Actions
Thymidine 5?-monophosphate p-nitrophenyl ester sodium salt is an artificial substrate marker for 5?-nucleotide phosphodiesterase enzyme activity. It is also used as a substrate for autotaxin (ATX, NPP2), which is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (NPP) enzyme family.
Packaging
25, 100, 250 mg in poly bottle
Substrates
A sensitive chromogenic substrate for venom phosphodiesterase. It is not hydrolyzed by bovine spleen phosphodiesterase.
| Quality Level | 200 |
|---|---|
| InChI key | PHNRUCBIIRECII-UHFFFAOYSA-N |
| InChI | 1S/C16H18N3O10P.Na.H/c1-9-7-18(16(22)17-15(9)21)14-6-12(20)13(28-14)8-27-30(25,26)29-11-4-2-10(3-5-11)19(23)24;;/h2-5,7,12-14,20H,6,8H2,1H3,(H,25,26)(H,17,21,2 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Solubility | water: 50 mg/mL |
| Form | powder |
| Assay | ≥98% (HPLC) |
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