DIPROVOCIM-1
Biochem/physiol Actions
Diprovocim-1 is a potent agonist of toll-like receptors TLR2 and TLR1 with an EC50 value of 100 pM. Diprovocim-1 was shown to synergize with anti-PD-L1 treatment, inhibiting tumor growth, generating long-term antitumor memory, and curing or prolonging survival of mice engrafted with the murine melanoma B16-OVA.
| Colour | white to beige |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | DMSO: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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