Biochem/physiol Actions
HS56 is a highly selective and potent dual Pim/DAPK3 inhibitor that significantly reduces contractile intensity and phosphorylation levels of myosin light chain (LC20) in rat caudal arterial smooth muscle strips. HS56 decreases blood pressure in spontaneously hypertensive mice without affecting heart rate.
| Colour | white to beige |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | DMSO: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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