Biochem/physiol Actions
NAMI-A is a ruthenium-based anticancer agent.
NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins. Nevertheless NAMI-A induces potent and selective cytotoxic effects in several leukemia cell lines. NAMI-A exhibits low toxicity for host tissues.
| Colour | faint red to dark brown |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Solubility | H2O: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% ruthenium (Ru) basis (elemental analysis) |
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