Biochem/physiol Actions
AH-7614 is a potent negative allosteric modulator (NAM) of the long-chain free fatty acid receptor FFA4 that prevents differentiation of a mouse mesenchymal stem cell line toward an adipocyte phenotype. AH-7614 (Compound 39) was first described as antagonist of FFA4 that blocks activation of FFA4 by polyunsaturated, Ω-6 fatty acid, linoleic acid and GSK137647A.
| Colour | white to beige |
|---|---|
| InChI key | OZCQEUZTOAAWDK-UHFFFAOYSA-N |
| InChI | 1S/C20H17NO3S/c1-14-10-12-15(13-11-14)25(22,23)21-20-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)20/h2-13,20-21H,1H3 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | DMSO: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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