Biochem/physiol Actions
BOP (N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt) is a potent and selective dual inhibitor of integrins alpha-4 beta-1 (A4β1) and alpha-9 beta-1 (A9β1) with Kd values in the picomolar range. BOP has been shown to preferentially mobilize hematopoietic stem cells (HSCs) and progenitors and to act synergistically with AMD3100.
| Colour | white to beige |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | H2O: 2 mg/mL, clear (warmed) |
| Form | powder |
| Assay | >97% (HPLC) |
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