GARENOXACIN MESYLATE MONOHYDRATE
Biochem/physiol Actions
Garenoxacin is a broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections. Garenoxacin has a low mutant prevention concentration and a narrow mutant selection window. Data shows that garenoxacin has anti-inflammatory properties. It significantly alleviates LPS-induced IL-8 production through the negative regulation of the ERK1/2 pathway both in the human airway epithelial cell line A549 and the monocyte cell line THP-1.
Packaging
10, 50 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | IGTHEWGRXUAFKF-NVJADKKVSA-N |
| InChI | 1S/C23H20F2N2O4.CH4O3S.H2O/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4;/h2,5-8,10-11,14,23,26 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: 10 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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