OTILONIUM BROMIDE

Descriptions

Biochem/physiol Actions

Otilonium bromide has the capability to prevent L-type Ca²⁺ channels and colonic contractile activity. It is a tolerable drug as it is absorbed poorly and has very less side effects.

Otilonium Bromide is a muscarinic receptor antagonist (antimuscarinic). Otilonium Bromide is a quaternary ammonium salt that exerts spasmolytic action selective on the distal gastrointestinal tract. It is used world-wide for the treatment of irritable bowel syndrome (IBS).

General description

Otilonium bromide is an antispasmodic. It contains a red color ACh (acetylcholine) like moiety bound to an aromatic system that ends with an octyl ether.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	white to beige
Quality Level	100
InChI key	VWZPIJGXYWHBOW-UHFFFAOYSA-N
InChI	1S/C29H42N2O4.BrH/c1-5-8-9-10-11-14-22-34-27-16-13-12-15-26(27)28(32)30-25-19-17-24(18-20-25)29(33)35-23-21-31(4,6-2)7-3;/h12-13,15-20H,5-11,14,21-23H2,1-4H3;1
Manufacturer	SIGMA-ALDRICH
Solubility	H2O: 5 mg/mL, clear (warmed)
Form	powder
Assay	≥98% (HPLC)