6-THIO-2-DEOXYGUANOSINE

6-THIO-2-DEOXYGUANOSINE

Stock Code: 3574715
Manufacturer Part No: SML1296-25MG
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Application


6-Thio-2?-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.


Biochem/physiol Actions


6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.


Packaging


5, 25 mg in glass bottle

Colourwhite to brown
Quality Level100
InChI keySCVJRXQHFJXZFZ-HSUXUTPPSA-N
InChI1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥97% (HPLC)

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