Biochem/physiol Actions
PA-824 is an anti-tuberculosis drug that exhibits multiple mechanism of action, including both cell wall inhibition and respiratory poisoning.
PA-824 is a pro-drug that has an effect on both replicating and non-replicating Mycobacterium tuberculosis. It is activated by deazaflavin (cofactor F420)-dependent nitroreducase.
PA-824 is an anti-tuberculosis drug.
Packaging
10, 50 mg in glass bottle
| Colour | white to brown |
|---|---|
| Quality Level | 100 |
| InChI key | ZLHZLMOSPGACSZ-NSHDSACASA-N |
| InChI | 1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 5 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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