Application
Retro-2 has been used to estimate retrograde trafficking of Shiga toxin subunit B (STxB)-Cy3.
Biochem/physiol Actions
Retro-2 is a non-toxic inhibitor of the endosome-to-Golgi retrograde transport that selectively protect cells from ricin, cholera toxin, and Shiga-like toxins, without affecting compartment morphology, endogenous retrograde cargos, or other trafficking steps.
Packaging
5, 25 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | BOAPXDSRULBILC-UHFFFAOYSA-N |
| InChI | 1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 10 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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