(S)-CPP SODIUM SALT >=96% (HPLC)
Biochem/physiol Actions
(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC50 = 6.3 µM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.
Packaging
5, 25 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | HMHPCHNNVOLTFC-QRPNPIFTSA-M |
| InChI | 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: 20 mg/mL, clear |
| Form | powder |
| Assay | ≥96% (HPLC) |
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