BNS-22, >=98% (HPLC)

Descriptions

Biochem/physiol Actions

BNS-22 is a derivative of natural product GUT-70 isolated from the stem bark of Calophyllum brasiliense exhibits antiproliferative activity against human cancer cells. It appears that BNS-22 is a specific DNA-topoisomerase II (TOPO2) catalytic inhibitor. BNS-22 does not induce DNA damage.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	white to beige
Quality Level	100
InChI key	LRPUQCTZOSTSGL-UHFFFAOYSA-N
InChI	1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: 2 mg/mL (clear solution; warmed)
Form	powder
Assay	≥98% (HPLC)