BAY-X-1005, >=98% (HPLC)
Biochem/physiol Actions
Bay-X-1005 is a potent inhibitor of 5-lipoxygenase activating protein (FLAP). Bay-X-1005 inhibits A23187-induced LTB4 production in human leucocytes with an IC50 value of 220 nM, and blocks IgE mediated airway contractions.
Packaging
5, 25 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | ZEYYDOLCHFETHQ-JOCHJYFZSA-N |
| InChI | 1S/C23H23NO3/c25-23(26)22(17-6-1-2-7-17)18-10-13-20(14-11-18)27-15-19-12-9-16-5-3-4-8-21(16)24-19/h3-5,8-14,17,22H,1-2,6-7,15H2,(H,25,26)/t22-/m1/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 5 mg/mL (clear solution) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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