Amorolfine hydrochloride, >=98% (HPLC)
Application
Amorolfine hydrochloride has been used as an antifungal agent.
Biochem/physiol Actions
Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis.
Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.
Packaging
10, 50 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | XZKWIPVTHGWDCF-KUZYQSSXSA-N |
| InChI | 1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+; |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: ≥5 mg/mL (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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