SR11237, >=98% (HPLC)
Application
SR11237 may be used in RXR-mediated cell signaling studies.
Biochem/physiol Actions
SR11237 and other ligands of retinoid X receptor (RXR) activate various nuclear receptors during development process. This produces malformations in Xenopus embryos, involving the anterior-posterior axis.1
SR11237 is a selective pan retinoid X receptor (RXR) agonist with no retinoid A receptor (RAR) activity.
Packaging
5, 25 mg in glass bottle
| Colour | white to off-white |
|---|---|
| Quality Level | 100 |
| InChI key | ZZUKALQMHNSWTK-UHFFFAOYSA-N |
| InChI | 1S/C24H28O4/c1-22(2)11-12-23(3,4)20-15-18(9-10-19(20)22)24(27-13-14-28-24)17-7-5-16(6-8-17)21(25)26/h5-10,15H,11-14H2,1-4H3,(H,25,26) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: >28 mg/mL (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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