KB-R7943, >=98% (HPLC), powder
Biochem/physiol Actions
KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.
Packaging
5, 25 mg in glass bottle
| Colour | off-white to tan |
|---|---|
| Quality Level | 100 |
| InChI key | WGIKEBHIKKWJLG-UHFFFAOYSA-N |
| InChI | 1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: >10 mg/mL |
| Form | powder |
| Assay | ≥98% (HPLC) |
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