THROMBOPOIETIN; HU-10UG

THROMBOPOIETIN; HU-10UG

Stock Code: 3571756
Manufacturer Part No: GF037
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Biochem/physiol Actions


The ED50 was determined by the dose-dependent stimulation of the proliferation of M07e cells is ≤1.0 ng/mL


Disclaimer


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


General description


Product Source: E.coli


TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. Chemicon′s Human TPO is a soluble 18.5 kDa protein containing 174 amino acid residues which comprises the receptor binding domain of the Mpl-ligand protein.


Legal Information


CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


Physical form


Lyophilized protein from 5mM Tris, pH 7.6, with no additives.


Storage and Stability


The lyophilized powder, though stable at room temperature, is best stored at -20°C. Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.5-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Reconstituted TPO should be stored in working aliquots at -20°C.

Quality Level100
ManufacturerSIGMA-ALDRICH
Impurities﹤0.1 ng/mg Endotoxin (of human TPO; 1 EU/µg)
Assay>98% (SDS-PAGE and HPLC)

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