FACADE (R)-EPC

Descriptions

Application

Facade^®-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.

Biochem/physiol Actions

Facade^® is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.

Facade^® EPC/FA-7 (3?-hydroxy-7?,12?-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.

Legal Information

Facade is a registered trademark of Avanti Polar Lipids, Inc.

Packaging

5 mL Amber Glass Screw Cap Vial (850539P-25mg)