N-DODECYL-BETA-D-MALTOSIDE (DDM 85%)
General description
This product is a more cost-effective alternative to Avandecrys® DDM that can be used for membrane protein extraction and purification. DDM is the most widely used detergent for the isolation and purification of GPCR′s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form
Legal Information
Avandecrys is a registered trademark of Avanti Polar Lipids, Inc.
Packaging
20 mL Clear Glass Screw Cap Vial (250520P-1g)
| InChI key | NLEBIOOXCVAHBD-QKMCSOCLSA-N |
|---|---|
| InChI | 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20- |
| Form | powder |
| Assay | >85% (contains ﹤15% alpha isomer) |
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